🧠 Major Milestone in iNPH Research: PENS Trial Published in NEJM

The Brain Signs Lab is excited to announce the publication of the PENS Trial in The New England Journal of Medicine, marking an important milestone for idiopathic normal-pressure hydrocephalus (iNPH) research and patient care. This international, randomized, placebo-controlled study demonstrated that shunt surgery leads to meaningful improvements in gait and balance for patients with iNPH. Dr. Abhay Moghekar served as Johns Hopkins site investigator, and Dr. Siavash Shirzadeh Barough played a key role as part of the imaging core. We are proud to have our team represented in this landmark publication and look forward to the continued impact of this work as additional data from the trial are released.

Access the full article here: https://www.nejm.org/doi/full/10.1056/NEJMoa2503109